AIDS Updates: Recent Advances and New Perspectives
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Significant progress in HIV prevention and control has been achieved worldwide. This book reviews emerging challenges and new opportunities for prevention. Chapters cover such topics as challenges in the media within the context of advancing technologies and societal perceptions, barriers to antiretroviral treatment and suggestions for improvement, opportunities in nanotechnology-based drug delivery systems, the central role of sexual and reproductive health in consolidating a human rights-based program, and much more. Client-focused models for integrating employment as a social determinant in the HIV/AIDS programs are discussed and recommended.
The Autoimmune Diseases
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The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P's" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.
The Borders of AIDS: Race, Quarantine, and Resistance
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As soon as US media and politicians became aware of AIDS in the early 1980s, fingers were pointed not only at the gay community but also at other countries and migrant communities, particularly Haitians, as responsible for spreading the virus. Evangelical leaders, public health officials, and the Reagan administration quickly capitalized on widespread fear of the new disease to call for quarantines, immigration bans, and deportations, scapegoating and blaming HIV-positive migrants?even as the rest of the world regarded the US as the primary exporter of the virus. In The Borders of AIDS, Karma Chávez demonstrates how such calls proliferated and how failure to impose a quarantine for HIV-positive citizens morphed into the successful enactment of a complete ban on the regularization of HIV-positive migrants?which lasted more than twenty years. News reports, congressional records, and AIDS activist archives reveal how queer groups and migrant communities built fragile coalitions to fight against the alienation of themselves and others, asserting their capacity for resistance and resiliency. Building on existing histories of HIV/AIDS, public health, citizenship, and immigration, Chávez establishes how politicians and public health officials treated different communities with HIV/AIDS and highlights the work these communities did to resist alienation.
Fungal Infections in Immunocompromised Hosts
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In this unique supplement, we have compiled several state-of-the-art topics that are based on lectures delivered by eminent mycology experts during the 37th ICHS meeting. We hope that the esteemed audience of the Journal of Fungi will enjoy and appreciate the ever-evolving and complex field of fungal infections in vulnerable hosts.
Lahita's Systemic Lupus Erythematosus
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Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries.
The Lung in Autoimmune Diseases
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The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, prognosis and risks to treatment, this book provides a comprehensive approach for the role of the lung in autoimmune diseases and the influence of autoimmune disease on the lung's functionality. In recent years, there is increasing knowledge in the field, including lung infection in early disease stages, mechanisms involved in lung damage, and new treatments. Recognition of lung involvement and implementation of some specific therapies is an important issue for clinicians dealing with systemic autoimmune diseases. Provides a comprehensive review of the different patterns of pulmonary involvement in systemic autoimmune diseases Describes new, targeted therapies for the treatment of systemic autoimmune diseases, including anti-fibrotics, biologics and vasodilators Gives insights on the prognosis of patients suffering from systemic autoimmune diseases Depicts better definitions of types of lung involvement in patients with an underlying systemic autoimmune disease
Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases
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The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.
Rethinking Diabetes: Entanglements with Trauma, Poverty, and HIV
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At the same time, Mendenhall asks us to unpack how social, cultural, and epidemiological factors shape people's experiences and why we need to take these differences seriously when we think about what drives diabetes and how it affects the lives of the poor.
Rheumatoid Arthritis
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Rheumatoid arthritis (RA) is a chronic autoimmune disease generating joint pain and damage in which inflammation plays a major role. RA joints are inflamed and stiff. Symptoms include joint swelling and warmth causing fatigue affecting life's health-related quality. Still, there are many other medical conditions that can also be associated with your symptoms and signs. This book is not a substitute for a diagnosis from a healthcare provider. Yet, understanding your symptoms and signs and educating yourself about health conditions is important and can contribute to having the healthiest possible life. Herein, Professor Hechmi Toumi offers an edited volume with detailed new information on RA pathogenesis and explains both approaches and treatment options: recent clinical research and traditional methods.
Rheumatoid Arthritis: a Systematic Approach
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Rheumatoid Arthritis: A systematic approach to Arthritis of Rheumatic Diseases provides readers with a simple but high quality diagnostic interpretation of clinical images of rheumatoid arthritis. The authors present a systematic approach to explaining the topics related to rheumatoid arthritis with the aid of medical images. Key Features: Presents information in the ABCDEGFG methodology (A: alignment, B: bone, C: cartilage, and D: distribution, E: extra-bone, F: further examination, and G: goal) Illustrates a broad range radiographic imaging techniques such as plain radiography, magnetic resonance imaging (MRI), CT, scintigraphy, PET-CT, ultrasound, and clinical photographs. Explains topics in a simple pictorial essay format The book is a simplified reference for medical students studying rheumatology and orthopedics as well as interns in radiology.
Rheumatoid Arthritis: Other Perspectives towards a Better Practice
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Rheumatoid Arthritis - Other Perspectives towards Better Practice sheds light on the disease process of rheumatoid arthritis as well as the disease's related comorbidities. Chapters cover such topics as immune-pathogenic theories, classification criteria, available composite measures of disease assessment, and latest available therapeutic approaches.
A Socio-criminological Analysis of the HIV Epidemic
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In the world of the 21st century, epidemics are common biological and social occurrences, with HIV perhaps emphasising this better than any other disease. Medical scientific research has undoubtedly made significant steps forward; meanwhile, the social research field is still in its initial stages, with many awaiting an equally auspicious response.A Socio-Criminological Analysis of the HIV Epidemic offers a comprehensive analysis of the multifaceted socio-criminological dimensions of the HIV epidemic and positively contributes to the ongoing sociological debate on infectious diseases. The author intends to create an independent epistemology of HIV to explicate the social forces that impact and determine the course and experience of the epidemic, while also seeking to reframe the popular discourse on HIV to reflect sociological conceptualisations. This latter step leads to the identification of the concept of social interaction as an appropriate tool for highlighting the complex social nature of this virus. The unprecedented challenge posed by the epidemic for the international community calls for global cooperation aimed at evaluating the diverse aspects of the issues that many actors in this tragic drama must deal with.Given its wide-reaching international appeal, this book is also recommended for those involved or interested in global health issues and infectious diseases. It will be of particular interest to medical researchers, health workers, social scientists, social workers, policymakers, humanitarian workers, HIV and human rights activists, and graduate students.
Systemic Lupus Erythematosus: Basic, Applied and Clinical Aspects
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This completely updated and expanded 2nd edition of Systemic Lupus Erythematosus, A Manual includes topics not covered previously with contributors who are at the forefront of each specific topic and with a global appeal. Each chapter is short and is presented critically with selected references, which should be valuable to a wider audience. This book combines basic with clinical science to help internists and specialists in the diagnosis and management of patients with SLE. It is a quick referral for people in the pharmaceutical industry in their efforts to bring much-needed drugs. It provides all the needed information to basic researchers old and new alike, who wish to enter the field of lupus and systemic autoimmunity in general.
Tackling the World's Fastest-Growing HIV Epidemic : More Efficient HIV Responses in Eastern Europe and Central Asia
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The Eastern Europe and Central Asia region has the world's fastestgrowing HIV epidemic. Although still concentrated, the epidemic has diversified, affecting several key populations in many countries. This change has increased the number of people in need, the ways the epidemic can spread, and the complexity of formulating an effective strategy to combat it. At the same time, international funding is insufficient to cover the growing need, and domestic plans to cover the funding gaps, in many cases, fall short. In this environment, the need to use data to make the best possible decisions about using available funds is essential. Tackling the World's Fastest-Growing HIV Epidemic tells the story of how, in 11 countries across Eastern Europe and Central Asia, small groups of decision-makers and experts came together to carry out innovative, groundbreaking analyses for each country. It details the steps these nations have taken to strengthen their HIV programs based on the findings while highlighting critical issues for the road ahead. In so doing, the book also shows the potential of what can be done with a mathematical model and how it can support real-life improvements in policy and more efficacious budget allocations. It is the record of a unique undertaking to improve public health investments that offers lessons for many communities.
Translational Autoimmunity: Treatment of Autoimmune Diseases Volume 2
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Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases.
Understanding Fibromyalgia: An Introduction for Patients and Caregivers
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Fibromyalgia is a chronic disorder associated with overall body pain and discomfort. Although the condition is not a variety of other neurological disorders or even arthritis, it possesses some of the same symptoms. There are an estimated 10 million Americans suffering with fibromyalgia, and estimates suggest that three to six percent of the world's population have symptoms of fibromyalgia. The medical costs of treatment coupled with lost productivity have been estimated in the billions of dollars. The good news is that fibromyalgia is not progressive and is not fatal. Many sufferers report that the symptoms can improve with treatment and time. This accessible introduction to the disorder helps educate both sufferers and caregivers alike to the symptoms, potential causes, treatments, and outcomes of fibromyalgia. Addressing both traditional and alternative approaches, Naheed Ali offers hope and guidance for those seeking both understanding and possible paths to recovery. He focuses not just on the science and medicine behind fibromyalgia, but also on living well with it after diagnosis. Offering tips for lifestyle modifications as well as advice for caregivers, family, and friends, he ultimately provides a responsive and hopeful guide to this often misunderstood condition.
Subject search terms: AIDS (Disease), Autoimmune diseases, Fibromyalgia, Gout, HIV infections, Rheumatoid arthritis, Systemic lupus erythematosus; Keyword search term: Auto-immune disorders