Cellular, Molecular, Physiological, and Behavioral Aspects of Traumatic Brain Injury
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Traumatic brain injury has complex etiology and may arise as a consequence of physical abuse, violence, war, vehicle collisions, working in the construction industry, and sports. Cellular, Molecular, Physiological, and Behavioral Aspects of Traumatic Brain Injury will improve readers' understanding of the detailed processes arising from traumatic brain injury. Featuring chapters on neuroinflammation, metabolism, and psychology, this volume discusses the impact of these injuries on neurological and body systems to better understand underlying pathways. This book will be relevant for neuroscientists, neurologists, clinicians, and anyone working to better understand traumatic brain injury.
Handbook of Traumatic Brain Injury and Neurodegeneration
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Holbourne's theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood 'punch drunk' syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy.This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.
Insomnia and Fatigue after Traumatic Brain Injury: A CBT Approach to Assessment and Treatment
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Insomnia and fatigue are two of the most frequent consequences after traumatic brain injury (TBI). About 30% of individuals suffer from chronic insomnia, an additional 20% have symptoms of insomnia, and up to 75% have significant and persistent fatigue. There is a strong empirical basis for the effectiveness of cognitive-behavioral interventions for the management of insomnia and fatigue in the general population and in other patient populations, and emerging research shows that these interventions seem applicable with similar benefits to people with TBI. Insomnia and Fatigue After Traumatic Brain Injury: A CBT Approach to Assessment and Treatment is written by a team of four scientist-practitioners in psychology who are experts in sleep medicine, cognitive-behavioral therapy for insomnia, and traumatic brain injury (TBI). Together they have authored this assessment and intervention manual for insomnia and fatigue, intended for clinicians working with the TBI population. Based on cognitive-behavioral principles, the manual integrates evidence-based interventions and techniques used by expert clinicians working with these populations. Throughout the development process, there has been an ongoing integration of the best available research, specialized clinical expertise, and knowledge transfer expertise: all of these perspectives were used to choose, revise, and format the content of the manual as to ensure that it would be most useful for the target audience.
Machine LearningMethods and Applications to Brain Disorders
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Machine Learning is an area of artificial intelligence involving the development of algorithms to discover trends and patterns in existing data; this information can then be used to make predictions on new data. A growing number of researchers and clinicians are using machine learning methods to develop and validate tools for assisting the diagnosis and treatment of patients with brain disorders. Machine Learning: Methods and Applications to Brain Disorders provides an up-to-date overview of how these methods can be applied to brain disorders, including both psychiatric and neurological disease. This book is written for a non-technical audience, such as neuroscientists, psychologists, psychiatrists, neurologists and health care practitioners.
New Therapeutic Strategies for Brain Edema and Cell Injury
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New Therapeutic Strategies for Brain Edema and Cell Injury, Volume 145, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this volume presenting interesting chapters on the Blood-brain barrier breakdown and brain edema formation in Alzheimer's disease, Blast brain Injury induced edema formation and therapeutic measures, Brain edema in Parkinson's disease. Novel therapeutic strategies, Brain edema and blood-brain barrier breakdown in sleep deprivation. Therapeutic potential of cerebrolysin, Differential cell injury induced by NMDA antagonist MK 801 in early age, Anesthetics influence Brain edema in concussive head injury, and more.
Obstetric Hemorrhage: Evidence-Based Management And Recent Advances
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