Anticoagulant Drugs by
Anticoagulant drugs are among the most frequently prescribed drugs in everyday clinical practice. In the past decades, several new direct oral anticoagulants were developed that changed the anticoagulant therapy landscape considerably. This book provides an extensive overview of all the known anticoagulants that can be useful for studying different aspects of the haemostatic system or as a starting point for new drug development. It is also a valuable tool for clinicians providing a description of the mode of action and management of therapy for anticoagulant drugs used in everyday clinical practice in different clinical settings, including direct oral anticoagulants dabigatran, rivaroxaban, apixaban and edoxaban.
Anticoagulation: Current Perspectives by
Thrombotic diseases are some of the leading causes of death in the world. Anticoagulation is a mainstay approach for the prophylaxis and treatment of thrombotic diseases. This book includes six chapters regarding the mechanisms of anticoagulation and its clinical value in different disease conditions. The first two chapters summarize the general information regarding anticoagulation and hypercoagulability/thrombophilia, and the remaining four chapters discuss the use of anticoagulation in different populations, including adult hospitalized surgical and medical patients, COVID-19 patients, patients with hepatic thrombotic disorders, and frail elderly patients with atrial fibrillation.
Anticoagulation Drugs: The Current State of the Art by 
Anticoagulation Management: A Guidebook for Pharmacists by
In addition to acting as a training guide for pharmacists, pharmacy residents and pharmacy students who seek to practice in areas associated with patients on anticoagulant therapy, the information presented within highlights the growing role of the pharmacist in these contexts. Readers will find useful information on anticoagulant management across all pharmacy practice areas, including the inpatient, ambulatory, emergency services and transitions of care settings. Particular attention is given to summarizing best practices and providing 'real world' examples of ways in which pharmacists can be involved in anticoagulation management and the impact of such involvement. In the first major section of the book, each chapter focuses on the role of the pharmacist in the management of medication with a specific type of anticoagulants (e.g. warfarin, heparin and target-specific oral agents) in various healthcare settings. A broader overview of the clinical management of anticoagulation therapy is provided in the second major section, including descriptions of the role of pharmacists in assessing venous thromboembolism risk, ensuring patients receive appropriate prophylactic therapy, and monitoring outcomes.
Anticoagulation Therapy: A Clinical Practice Guide by
Although highly effective in preventing thromboembolic events, the safe management of anticoagulant therapy continues to be a major challenge, requiring constant monitoring and coordinated models of patient-centered care. Anticoagulation Therapy: A Clinical Practice Guide, Second Edition, helps take the guesswork out of managing these therapies and provides essential recommendations. This revised and expanded edition includes: Extensive new information on the direct oral anticoagulants (DOACs) Expanded information on anticoagulant reversal and expanded use of prothrombin complex concentrates New chapters on the use of anticoagulants in special patient populations, the use of anticoagulants in patients with mechanical devices, anticoagulation care delivery standards, regulatory issues, and more Four new appendices on the effect of DOACs on chemotherapy, nutritional influences, types of central nervous system hemorrhage, and use of anticoagulation in patients with coagulopathies
Antiplatelet Therapy in Cardiovascular Disease by
Edited by a team of the world's leading interventional cardiologists and educators, this new book is created with an eye to giving the reader a solid, practical, and clinically focused understanding of this important class of drugs, from basic science to a clear-headed discussion of complex topics such as combination therapies, drug-to-drug interactions, and resistance to antiplatelet agents. This important new book: Begins with a concise but thorough discussion of platelet biology and pathophysiology so that readers understand how antiplatelet agents work and why they produce such a varied range of complications, from minor GI upset to potentially life-threatening conditions such as neutropenia, a critical shortage of white blood cells. Thoroughly covers platelet function testing, including novel techniques. Clarifies current best practice regarding the use of antiplatelet agents in both chronic and acute cardiovascular disease. Reviews all types of antiplatelet agents - from aspirin to recently approved drugs - including indications, clinical outcomes, and side effects. Written by an international "who's who" of experts in the field, Antiplatelet Therapy in Cardiovascular Disease also includes an entire section covering the use of antiplatelet drugs in PCIs, including percutaneous valve repair, which makes this text particularly essential to interventional cardiologists.
Atrial Fibrillation and Percutaneous Coronary Intervention: A Case-Based Guide to Oral Anticoagulation, Antiplatelet Therapy and Stenting by
This book considers paradigmatic clinical cases in order to cast light on key issues relating to elective or emergency stent implantation and the use of oral anticoagulation (OAC) in patients with atrial fibrillation. The topics addressed include the optimal periprocedural antithrombotic treatment (uninterrupted vs interrupted OAC, intraprocedural use of heparin and glycoprotein IIb/IIIa inhibitors, etc.), the most appropriate type of stent (bare metal vs drug eluting vs "bioactive"), the optimal regimen (e.g., triple therapy of OAC, aspirin, and clopidogrel vs the combination of OAC and a single antiplatelet agent), and the most suitable duration of the antithrombotic treatment prescribed at discharge (1 vs 6-12 months). The case-based management recommendations will be of wide practical value in the current health care context, where percutaneous coronary intervention is available even to patients with relevant co-morbidities, such as those warranting long-term OAC, and the indications for OAC are much broader than in the past. The book will appeal especially to clinical and interventional cardiologists, internal medicine specialists, hematologists, and family physicians and will also be of interest to cardiology and internal medicine residents and fellows.
Infusion Therapy Made Incredibly Easy by
Get a thorough grounding in delivering safe, effective infusion therapy with the friendly support and technical guidance of the newly updated Infusion Therapy Made Incredibly Easy! ®, 5th edition. This complete how-to on administering and monitoring different IV medications delivers clear direction on vital concepts, terms, and techniques--backed by numerous illustrations, confidence-building humor, and expert insights. Offering clear, concise direction for nursing students, this popular Incredibly Easy!® text is also the ideal refresher for nurses and all practitioners learning best practices for a range of infusion therapies. Get the skills and know-how needed to administer infusion therapy successfully... NEW and completely revised/updated content with the latest infusion therapy techniques Easy-to-read, easy-to-remember guidance for students and practitioners lacking IV experience Start-to-finish directions and concise explanations on areas such as: Preparation Access sites Equipment use and management IV starting techniques, including line insertion Handling complications Infusion therapy using peripheral veins Infusion therapy requiring central venous access Parenteral nutrition Antineoplastic, biologic, and chemotherapy Discontinuing an IV Managing hypothermia, hypernatremia, calcemia, and kalemia Special considerations for pediatric, geriatric, and home care patients Legal issues and professional standards Dozens of colorful diagrams, photos and illustrations explain skills and core concepts, including: Delivery methods Flow rates Infusion fluids and medications Monitoring and documentation Transfusion therapy Special features include: Just the facts - a quick summary of each chapter's content "Nurse Joy" and "Jake" - offer clear explanations, vital care reminders, and expert insight on interventions and problem-solving Quick quiz - multiple-choice questions after each chapter to help you retain knowledge That's a wrap! - summary of key information for quick chapter reviewBest practice - evidence-based standards for administering and monitoring infusion therapyWarning - possible risks or complications Running smoothly - pointers on keeping both patient and equipment problem-free Memory jogger - anecdotes and memory tricks to help you retain vital content Practice Makes Perfect - end-of-book NCLEX practice questions for solid exam preparation
Intravenous Therapy Administration: a Practical Guide by
This handy book, written by the author of the very popular Venepuncture and Cannulation: A Practical Guide, offers step-by-step guidance in how to administer intravenous fluids and medicines. It will be equally helpful, whether you are already practising.
Novel Therapeutic Targets for Antiarrhythmic Drugs by
PROFILES POTENTIAL TREATMENT APPROACHES FOR CARDIAC ARRHYTHMIAS Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, Novel Therapeutic Targets for Antiarrhythmic Drugs presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology. Written by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections: Section One comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs. Section Two addresses safety pharmacology, including the concept of "repolarization reserve," safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs. Section Three describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets. Section Four describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids). Offering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, Novel Therapeutic Targets for Antiarrhythmic Drugs provides an important resource to advanced students, working researchers, and busy professionals alike.
Oral Anticoagulation Therapy: Cases and Clinical Correlation by
Given the amount and complexity of information surrounding the the target specific oral anticoagulants a lengthy didactic educational format has the potential to be overwhelming to the reader and difficult to translate and apply to direct patient care. The proposed book will educate clinicians utilizing a series of clinical cases to simultaneously develop the readers' knowledge base, problem-solving skills, and practically apply their new knowledge to a variety of clinical situations. These will be short focused case presentations that provide critical information and pose questions to the reader at key points in the decision making process. The cases will be relevant to what clinicians will encounter not only on a daily basis, but also reflective of scenarios that clinicians will not encounter regularly, but that they will have to act upon (e.g. a bleeding patient, patient scheduled for elective or emergent procedure, patient with changing renal function, patient on drugs that have a plausible yet unstudied drug interaction with a target specific oral anticoagulant etc). Included in the case studies will be evidence-based discussions (with appropriate references) that provide immediate feedback on the different treatment alternatives that were offered. The case studies will be designed to instruct the reader how to select and effectively utilize the most appropriate agent for a given clinical scenario. They will focus on key features of the target specific oral anticoagulants, what they have in common, how they are unique from each other, as well as illustrating the clinical decision process one should take when selecting an agent or managing a patient already receiving one of the target specific oral agents. ​
Pediatric Injectable Drugs: The Teddy Bear Book by
If you work with children, you must have this book. For more than two decades, Pediatric Injectable Drugs (The Teddy Bear Book) has served an important and continuing need for reliable evidence-based information specific to pediatric injectable drugs, including all drugs commonly used in the treatment of infants and children from neonates to adolescents, with age-specific dosing and administration guidelines throughout. ASHP's classic reference on pediatric drugs is now fully revised with the eleventh edition of Pediatric Injectable Drugs. Included in this edition are 15 new monographs, with 241 monographs in total. Each monograph now includes a new category on obesity dosing. All information is compiled in an evidence-based manner from the primary literature, including case reports, observational reports, and comparative trials. As with previous editions, the structure of each of the drug monographs covers the following areas: Brand names. Medication error potential. - Contraindications and warnings. Infusion-related cautions. Age-specific dosage. Dosage adjustment in organ dysfunction. Maximum dosage. Additives. Suitable diluents. Maximum concentrations. Preparation and delivery. IV push. Intermittent infusion. Continuous infusion. Other routes of administration. Comments. When it comes to pediatric injectable drugs, valid safety and efficacy research can be hard to locate: this indispensable reference changes all that.
Platelets by
Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource.
Heart—Pathophysiology, Anticoagulants (Medicine), Arrhythmia, Blood platelets, Cardiovascular system, Heart—Diseases, Hypertension, Intravenous therapy, Myocardial depressants